Dom DeLuise

A widowed field mouse must move her family -- including an ailing son -- to escape a farmer's plow. Aided by a crow and a pack of superintelligent, escaped lab rats, the brave mother struggles to transplant her home to firmer ground.

Some time after the Mousekewitz's have settled in America, they find that they are still having problems with the threat of cats. That makes them eager to try another home out in the west, where they are promised that mice and cats live in peace. Unfortunately, the one making this claim is an oily con artist named Cat R. Waul who is intent on his own sinister plan.

When a casino-owning dog named Charlie is murdered by his rival Carface, he finds himself in Heaven. Wanting to get back at his killer, he cons his way back to the living with the warning that doing so damns him to Hell. Once back, he teams with his old partner, Itchy, to prep his retaliation. He stumbles upon an orphan girl who can talk to the animals, thus allowing him to get the inside info on the races to ensure his wins to finance his plans. However, all the while, he is still haunted by nightmares of what's waiting for him on the other side unless he can prove that he is worthy of Heaven again.

Putting its own 'twist' on the story of Oliver Twist, the orange runt of a litter of kittens must fight for survival on the rough streets on New York City, finding unlikely friends in the dogs owned by a down-on-his luck man named Fagin. Soon, Oliver and his new band of comrades must fight for survival when Fagin is unable to pay his debts.

A cross-country road race is based on an actual event, the Cannonball Baker Sea to Shining Sea Memorial Trophy Dash, organized by Brock Yates to protest the 55 mph speed limit then in effect in the U.S. The Cannonball was named for Erwin G. "Cannonball" Baker, who in the roaring 20's rode his motorcycle across the country. Many of the characters are based on ruses developed by real Cannonball racers over the several years that the event was run.

The Bandit goes on another cross-country run, transporting an elephant from Florida to Texas. And, once again, Sheriff Buford T. Justice is on his tail.